Ionone Derivatives from the Mycelium of Phellinus linteus and the Inhibitory Effect on Activated Rat Hepatic Stellate Cells

Author's response to reviews Title: Immunomodulatory effect of water soluble extract separated from mycelium of Phellinus linteus on experimental atopic dermatitis Authors: JI-Sun Hwang ([email protected])

Author's response to reviews Title: Immunomodulatory effect of water soluble extract separated from mycelium of Phellinus linteus on experimental atopic dermatitis Authors:

Inhibition of IgE-dependent Mouse Triphasic Cutaneous Reaction by a Boiling Water Fraction Separated from Mycelium of Phellinus linteus

Phellinus linteus, a mushroom, contains constituents that exhibit potent antitumor effects through activating immune cells. Recently, anti-inflammatory and anti-allergic properties of P. linteus extracts have also been implicated. In the present study, therefore, we separated the constituents of mycelium of P. linteus into five fractions-chloroform-soluble (CF), ethyl acetate-soluble (EA), meth...

Biol. Pharm. Bull. 29(7) 1360—1365 (2006)

sensitivity, such as allergy and anaphylaxis. In response to the IgE-dependent and IgE-independent stimuli, mast cells elicit degranulation, which results in releasing various mediators, such as histamine and an array of inflammatory cytokines. Histamine, a main content of granules in mast cells, exerts many effects related to the acute phase of immediate hypersensitivity, including vasodilatat...

Immunomodulatory effect of water soluble extract separated from mycelium of Phellinus linteus on experimental atopic dermatitis

BACKGROUND Complementary and alternative medicine (CAM) is becoming a popular treatment for modulating diverse immune disorders. Phellinus linteus (P. linteus) as one of the CAMs has been used to modulate cancers, inflammation and allergic activities. However, little evidence has been shown about its underlying mechanism of action by which it exerts a beneficial role in dermatological disease i...